Bordetella pertussis toxin (50ug)
Bordetella pertussis toxin (50ug) (QTX30108-A) is a purified native pertussis toxin from Bordetella pertussis, in lyophilised form for ease of shipping, activity tested in a CHO cluster assay. Greater than 98% purity from Q-TOX™ .
Bordetella pertussis toxin has been developed in response to increasing pressure on the IVD industry to supply highly specific, cost-effective antibody capture systems, which are needed for monitoring vaccination programmes. FHA, a major cause of false results, is removed from the preparation by two rounds of chromatography. Bordetella pertussis is grown in batch culture, then the supernatant harvested and concentrated. Several rounds of chromatography are used to purify the native toxin to a very high level and with minimal lot-to-lot variation. CHO cell assays demonstrate a clustering concentration of between 0.01 and 0.005 ng/ml. The toxin is offered in lyophilized format, but is also produced in glycerol or liquid formulation depending on customer desire. Our QTX30108-A vials are particularly useful for academic labs seeking to use pertussis toxin as a research reagent.
For bulk quantities up to 100mg, we offer a liquid version of the toxin which saves the need for resuspension and also performs maximally in ELISA plate and IVD kit format.