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Coatest® APC Resistance-V-S (Genotype)

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Coatest® APC Resistance-V-S (Genotype) (82313863) is an APTT-based kit for screening of Factor V (FV)-related APC resistance (40 – 80 determinations). Manufactured by Chromogenix.

Product Brand:
Product Code: 82313863
Description

An APTT-based kit for screening of factor V-related APC resistance. High discrimination between genotypes with 100% sensitivity for FV:Q506. Reduces need for PCR determination and applicable to anticoagulant treated patients.The high sensitivity and specificity of the test for the factor V:Q506 mutation is obtained by prediluting the sample plasma with an excess of V-DEF Plasma. The test design makes it possible to discriminate between heterozygous and homozygous factor V genotypes. It also allows for analysis of plasma from patients on heparin or oral anticoagulant therapy.

One volume of plasma is prediluted with four volumes of V-DEF Plasma. The dilution is then incubated with the APTT reagent for a standard period of time. Coagulation is triggered by the addition of CaCl2 in the absence and presence of exogenous APC and the time for clot formation is recorded.

Product Specification
Specification Type
Specification Value
Product Range
Product Code
82313863
Product Name
Coatest® APC Resistance-V-S (Genotype)
Product Category
Product Brand
Product Analyte or Application
Product Size
1 x 40 tests
Product Storage
2°C to 8°C

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