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BIOPHEN™ DTI

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BIOPHEN™ DTI (220202) is a Chromogenic method for Direct Thrombin Inhibitors (DTI) assay. Manufactured by HYPHEN BioMed.

Product Brand:
Product Code: 220202
Description

BIOPHEN™ DTI is a chromogenic method based on the inhibition of a constant and in excess amount of thrombin (FIIa), by the tested Dabigatran or DTI. The hydrolysis of a thrombin specific chromogenic substrate (CS-01(81)), by the residual thrombin, releases the pNA from the substrate. The amount of pNA released (measured at 405 nm) is proportional to the residual thrombin activity. There is an inverse linear relationship between the concentration of Dabigatran (or DTI) and color development. [DTI] + [FIIa (excess)]  [FIIa-DTI] + [residual FIIa] [FIIa (residual)] + Substrate  Peptide + pNA

Product Specification
Specification Type
Specification Value
Product Range
Product Code
220202
Product Name
BIOPHEN™ DTI
Product Category
Product Brand
Product Analyte or Application
Product Size
2 x 2.5 ml
Product Storage
2°C to 8°C

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