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Chromogenic Substrates in Haemostasis
Chromogenic substrates are small synthetic peptides which mimic the natural substrate of the enzyme and have a detector chromophore, typically para-nitroaniline (pNA), attached to the cleavage site. Enzymatic cleavage releases pNA and results in a colour change, which can be followed spectrophotometrically and is proportional to the activity of the enzyme. The concept of chromogenic […]
Pathogen Diagnostics Tips & Tricks
OPTIMAL ASSAY SELECTION FOR DIAGNOSTIC PARASITOLOGY & MYCOLOGY Conventional diagnostic methods (e.g., faecal egg count, blood smear examinations) rely on the presence of parasite, eggs, fungus, or spores in the patient sample and are often time consuming, subjective, and demand high expertise. Serology methods are gradually becoming a new standard for clinical diagnostics. They harness […]