Like the notes of a song, epigenetic marks regulate the symphony of gene expression that determines which genes are expressed and which genes are silenced. Changes in these epigenetic marks – methylation, acetyation and phosphorylation – can alter the interaction of the DNA to the histone complex found within the nucleosome and as a result enact profound changes in gene expression. High quality reagents for the study of these epigenetic marks are available from 21st Century Biochemicals that include: epigenetics peptides and antibodies, custom antibodies, antibodies to selected targets, bioactive peptides and apelin and apelin analogues. All peptides are sequence confirmed using MS CheckTM and high end mass spectrometry.
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